Naval Support Activity Hampton Roads is a United States Navy Echelon 4 regional support commander that is responsible to Navy Region Mid-Atlantic for the operation and maintenance of the installation of the same name that it is headquartered on. Adjacent to, but separate from Naval Station Norfolk, NSA Hampton Roads has the largest concentration of fleet headquarters administrative and communication facilities outside of Washington, D.C., including the headquarters for United States Fleet Forces Command, Naval Reserve Forces Command and United States Marine Corps Forces Command, along with components of the Joint Chiefs of Staff, and the home campus for the Joint Forces Staff College. NSA Hampton Roads is also home to NATO’s Joint Force Command Norfolk and NATO's Allied Command Transformation.

Navy Region Mid-Atlantic is one of eleven current naval regions responsible to Commander, Navy Installations Command for the operation and management of Naval shore installations in Wisconsin, Illinois, Michigan, Indiana, Ohio, Kentucky, North Carolina, Virginia, West Virginia, Maryland, Delaware, Pennsylvania, New Jersey, New York, Connecticut, Rhode Island, Massachusetts, Vermont, New Hampshire, and Maine.