Neder-Betuwe is a municipality in the province of Gelderland, in the east of the Netherlands. On 1 April 2003, it was established as the new name of the redivided municipality of Kesteren. Neder-Betuwe counted 25,042 inhabitants on 1 January 2022.

Gelderland, also known as Guelders in English, is a province of the Netherlands, occupying the centre-east of the country. With a total area of 5,136 km2 (1,983 sq mi) of which 176 km2 (68 sq mi) is water, it is the largest province of the Netherlands by land area, and second by total area. Gelderland shares borders with six other provinces and the German state of North Rhine-Westphalia.