Route 10 is a 23.51 mi (37.84 km) state highway in the northern part of the U.S. state of New Jersey. It runs from an intersection with U.S. Route 46 in Roxbury Township, Morris County, east to County Route 577 /CR 677 in West Orange, Essex County. Route 10 is a major route through northern New Jersey that runs through Ledgewood, East Hanover, and Livingston. It is a four-lane highway for most of its length with the exception of the easternmost part of the route. Route 10 features intersections with many major roads including Route 53 and US 202 in Morris Plains and Interstate 287 (I-287) in Hanover Township.

U.S. Route 46 (US 46) is an east–west U.S. Highway completely within the state of New Jersey, running for 75.34 mi (121.25 km), making it the shortest signed, non-spur U.S. Highway. The west end is at an interchange with Interstate 80 (I-80) and Route 94 in Columbia, Warren County, on the Delaware River. The east end is in the middle of the George Washington Bridge over the Hudson River in Fort Lee, Bergen County, while the route is concurrent with I-95 and US 1-9. Throughout much of its length, US 46 is closely paralleled by I-80. US 46 is a major local and suburban route, with some sections built to or near freeway standards and many other sections arterials with jughandles. The route runs through several communities in the northern part of New Jersey, including Hackettstown, Netcong, Dover, Parsippany-Troy Hills, Wayne, Clifton, Ridgefield Park, Palisades Park, and Fort Lee. It crosses over the Upper Passaic River at several points. The road has been ceremonially named the United Spanish–American War Veterans Memorial Highway.