Route 29 is a state highway in the U.S. state of New Jersey. Signed north-south, it runs 34.76 mi (55.94 km) from an interchange with Interstate 295 (I-295) in Hamilton Township in Mercer County, where the road continues east as I-195, northwest to Route 12 in Frenchtown, Hunterdon County. Between the southern terminus and I-295 in Ewing Township, the route is a mix of freeway and expressway that runs along the Delaware River through Trenton. This section includes a truck-restricted tunnel that was built along the river near historic houses and Riverview Cemetery. North of I-295, Route 29 turns into a scenic and mostly two-lane highway. North of the South Trenton Tunnel, it is designated the Delaware River Scenic Byway, a New Jersey Scenic Byway and National Scenic Byway, that follows the Delaware River in mostly rural sections of Mercer County and Hunterdon County. The obsolete Delaware & Raritan Canal usually stands between the river and the highway. Most sections of this portion of Route 29 are completely shaded due to the tree canopy. Route 29 also has a spur, Route 129, which connects Route 29 to U.S. Route 1 (US 1) in Trenton.

Interstate 295 (I-295) in Delaware, New Jersey, and Pennsylvania is an auxiliary Interstate Highway, designated as a bypass around Philadelphia, Pennsylvania, and a partial beltway of Trenton, New Jersey.