Route 33 is a state highway in the central part of the US state of New Jersey. The highway extends 42.03 miles (67.64 km), from an interchange with U.S. Route 1 (US 1) in Trenton, Mercer County, east to an intersection with Route 71 in Neptune, Monmouth County. Route 33 is a major route through central New Jersey, as it runs from the greater state capital area in the Delaware Valley region, through a mixture of farmland, housing, and commercial developments in the lower Raritan Valley region, en route to the greater Asbury Park area on the Jersey Shore. The route traverses through historic towns such as Hightstown, Monroe, Manalapan, Freehold, and Tinton Falls. There are several intersections on Route 33 with future developments.

U.S. Route 1 (US 1) is a U.S. Route which parallels the East Coast of the United States, running from Key West, Florida, in the south to Fort Kent, Maine, at the Canadian border in the north. Of the entire length of the route, 66.06 miles (106.31 km) of it runs through New Jersey. It enters the state from Pennsylvania on the Trenton–Morrisville Toll Bridge over the Delaware River in the state capital of Trenton, running through the city on the Trenton Freeway. From here, US 1 continues northeast as a surface divided highway through suburban areas, heading into Middlesex County and passing through New Brunswick and Edison. US 1 merges with US 9 in Woodbridge, and the two routes continue through northern New Jersey as US 1/9 to the George Washington Bridge over the Hudson River in Fort Lee. At this point, the road continues into New York City along with I-95.