Route 53 is a state highway in Morris County in the U.S. state of New Jersey. It runs 4.66 mi (7.50 km) from U.S. Route 202 in Morris Plains north to Bloomfield Avenue in Denville Township. The route, which is a two-lane undivided highway most of its length, intersects with Route 10, Interstate 80, and U.S. Route 46. For most of its length, the route runs a short distance to the east of New Jersey Transit's Morristown Line. It passes through industrial areas and wooded residential neighborhoods along its route.

U.S. Route 202 (US 202) is a spur route of US 2. It follows a northeasterly and southwesterly direction stretching from Delaware in the south to Maine in the north and traveling through the states of Pennsylvania, New Jersey, New York, Connecticut, Massachusetts, and New Hampshire. The highway has borne the number 202 since at least 1936. Before this, sections of the highway were designated U.S. Route 122, as it intersected US 22 in New Jersey. Its current designation is based on its intersection with I-395 and SR 15 near US 2 in Maine, but it does not have a direct connection with US 2.