The 45th congressional district of New York was a congressional district for the United States House of Representatives in New York. It was created in 1945 and eliminated as a result of the 1950 census. For the entirety of its existence it was represented by Daniel A. Reed who was redistricted into the 43rd district after its demise.

Daniel Alden Reed was an American college football player, coach, and U.S. Representative from the state of New York. Reed was attorney for the excise department of New York from 1903 to 1909. He served in the House of Representatives as a Republican from 1919 until his death in Washington, D.C., on February 19, 1959.