The New York Biltmore Hotel was a luxury hotel at 335 Madison Avenue in Midtown Manhattan, New York City. The hotel was developed by the New York Central Railroad and the New York, New Haven and Hartford Railroad and operated from 1913 to 1981. It was one of several large hotels developed around Grand Central Terminal as part of Terminal City. The Biltmore was designed in the Italian Renaissance Revival style by Warren and Wetmore, one of the firms involved in designing Grand Central. Although the hotel's steel frame still exists, the hotel itself was almost entirely demolished and replaced by an office building in the early 1980s.

The Hyatt Grand Central New York is a hotel located at 109 East 42nd Street, adjoining Grand Central Terminal, in the Midtown Manhattan neighborhood of New York City. It operated as the 2,000-room Commodore Hotel between 1919 and 1976, before hotel chain Hyatt and real estate developer Donald Trump converted the hotel to the 1,400-room Grand Hyatt New York between 1978 and 1980. As of 2019, the hotel is planned to be replaced with a skyscraper named Project Commodore.