New York State Route 145 (NY 145) is a state highway in eastern New York in the United States. The highway extends for 47 miles (76 km) from NY 23 in the Greene County town of Cairo to U.S. Route 20 (US 20) in the Schoharie County town of Sharon. Along the way, NY 145 intersects NY 30 in Middleburgh and Interstate 88 (I-88) east of Cobleskill. NY 145 is a two-lane highway its entire length, with a passing lane on hills leaving Middleburgh in both directions. The route follows parts of the Susquehannah Turnpike from Cairo through East Durham and west.

New York State Route 23 (NY 23) is an east–west state highway in the eastern portion of New York in the United States. It extends for 156.15 miles (251.30 km) from an intersection with NY 26 in the Central New York town of Cincinnatus in Cortland County to the Massachusetts state line in the Berkshire Mountains, where it continues east as that state's Route 23. Along the way, it passes through many communities, including the cities of Norwich and Oneonta. Outside of the communities, the route serves largely rural areas of the state and traverses the Catskill Mountains in the state's Central New York Region. NY 23 crosses the Hudson River at Catskill via the Rip Van Winkle Bridge.