New York State Route 146 (NY 146) is a state highway in the Capital District of New York in the United States. It extends for 43 miles (69 km) from Gallupville at NY 443 to near Mechanicville at U.S. Route 4 (US 4) and NY 32. NY 146 is a major thoroughfare in the city of Schenectady, just outside Albany. Most of the route follows an east–west alignment; however, the middle third of the route between Guilderland and Clifton Park runs in a more north–south manner in order to serve Schenectady. At one time, NY 146 had three spur routes; only one—NY 146A—still exists.

New York State Route 443 (NY 443) is an east–west state highway in the Capital District of New York in the United States. The route begins at an intersection with NY 30 in the town of Schoharie and ends 33.44 miles (53.82 km) later at a junction with U.S. Route 9W (US 9W) and US 20 in the city of Albany. It ascends the Helderberg Escarpment in the towns of Berne and New Scotland. Within the town of Bethlehem and the city of Albany, NY 443 is known as Delaware Avenue.