New York State Route 352 (NY 352) is a state highway in the Southern Tier of New York in the United States. It generally parallels the Southern Tier Expressway from the village of Riverside (exit 45) east through the city of Corning to the city of Elmira (exit 56). The portion of NY 352 west of the hamlet of Big Flats was once part of NY 17; the rest was originally New York State Route 17E. Construction of and improvements to the Southern Tier Expressway have resulted in extensions of NY 352, primarily along the former NY 17 right-of-way.

New York State Route 17 (NY 17) is a major state highway that extends for 397 miles (638.91 km) through the Southern Tier and Downstate regions of New York in the United States. It begins at the Pennsylvania state line in Mina and follows the Southern Tier Expressway east through Corning to Binghamton and the Quickway from Binghamton east to Woodbury, where it turns south to follow the Orange Turnpike to the New Jersey state line near Suffern, where it connects to New Jersey Route 17. From the Pennsylvania border to the village of Waverly and from Binghamton to Windsor, NY 17 is concurrent with Interstate 86 (I-86). Eventually, the entire east–west portion of NY 17 from the Pennsylvania border to Woodbury will become I-86 as projects to upgrade the route to Interstate Highway standards are completed.