New York State Route 38 (NY 38) is a north–south state highway in the Finger Lakes region of New York in the United States. Its southern terminus is at an intersection with NY 96 in the town of Owego in Tioga County. The northern terminus is at a junction with NY 104A in the town of Sterling in Cayuga County. NY 38 is a two-lane local road for most of its length. The route is the main access road to parts of Auburn, Dryden, Newark Valley and Port Byron. It passes through mountainous terrain in Tioga and Cortland counties, but the terrain levels out as it heads through the Finger Lakes area and Cayuga County.

Auburn is a city in Cayuga County, New York, United States. Located at the north end of Owasco Lake, one of the Finger Lakes in Central New York, the city had a population of 26,866 at the 2020 census. It is the largest city of Cayuga County, the county seat, and the site of the maximum-security Auburn Correctional Facility, as well as the William H. Seward House Museum and the house of abolitionist Harriet Tubman.