New York State Route 85 (NY 85) is a state highway in Albany County, New York, in the United States. It is 26.49 miles (42.63 km) in length and runs from CR 353 in Rensselaerville to Interstate 90 (I-90) exit 4 in Albany. It also has a loop route, NY 85A, which connects NY 85 to the village of Voorheesville. The portion of NY 85 north of NY 140 to the Bethlehem–Albany town/city line is known as the Slingerlands Bypass. From there north to I-90, the road is a four-lane freeway named the Crosstown Arterial.

Interstate 90 (I-90) is a part of the Interstate Highway System that runs from Seattle, Washington, to Boston, Massachusetts. In the US state of New York, I-90 extends 385.48 miles (620.37 km) from the Pennsylvania state line at Ripley to the Massachusetts state line at Canaan, and is the second-longest highway in the state after New York State Route 17 (NY 17). Although most of the route is part of the tolled New York State Thruway, two non-tolled sections exist along I-90. Within New York, I-90 has a complete set of auxiliary Interstates, which means that there are Interstates numbered I-190 through I-990 in the state, with no gaps in between. For most of its length in New York, I-90 runs parallel to the former Erie Canal route, NY 5, US Route 20 (US 20) and the CSX Transportation railroad mainline that traverses the state.