Newport Central bus station is a bus terminus and interchange located in the city centre, Newport, South Wales. It is the largest road transport hub for public services in the county. It is situated on the Newport Market site and the adjacent Friars Walk site.

Newport city centre is traditionally regarded as the area of Newport, Wales bounded by the west bank of the River Usk, the George Street Bridge, the eastern flank of Stow Hill and the South Wales Main Line. Most of the city centre is contained within two conservation areas: the central area and the area around Lower Dock Street. Most of the city centre is located in the Stow Hill district.