Nibbles is a fictional character from the Tom and Jerry cartoon series. He is the little, blue/gray, diaper-wearing orphan mouse whose cartoon debut came in the 1946 short The Milky Waif. Tuffy was later featured in the 1949 Academy Award-winning short The Little Orphan, as well as Two Little Indians and The Two Mouseketeers.

Tom and Jerry is an American animated media franchise and series of comedy short films created in 1940 by William Hanna and Joseph Barbera. Best known for its 161 theatrical short films by Metro-Goldwyn-Mayer, the series centers on the rivalry between the titular characters of a cat named Tom and a mouse named Jerry. Many shorts also feature several recurring characters.