Nickel Plate Road 759 is a class "S-2" 2-8-4 "Berkshire" type steam locomotive built in 1944 by the Lima Locomotive Works in Lima, Ohio as a member of the S-2 class for the New York, Chicago & St. Louis Railroad, commonly referred to as the "Nickel Plate Road". Built as a fast freight locomotive, No. 759 served the Nickel Plate until being retired in 1959 and placed into storage. In 1965, No. 759 was purchased by F. Nelson Blount for display in his Steamtown, U.S.A. collection in North Walpole, New Hampshire. The locomotive was restored to operating condition in 1967 by New York commodity broker Ross Rowland for use in hauling his Golden Spike Centennial Limited, a special commemorative train that celebrated the 100th anniversary of the completion of the Transcontinental Railroad in 1969. Afterwards, No. 759 pulled numerous excursions for Ross Rowland and Steamtown until being retired once more and placed back on display in 1977. As of 2023, the locomotive remains on static display at the Steamtown National Historic Site in Scranton, Pennsylvania, and sibling engine No. 765 continues to operate in mainline excursion service.

The New York, Chicago and St. Louis Railroad, abbreviated NYC&St.L, was a railroad that operated in the mid-central United States. Commonly referred to as the "Nickel Plate Road", the railroad served parts of the states of New York, Pennsylvania, Ohio, Indiana, Illinois, and Missouri. Its primary connections occurred in Buffalo, Chicago, Cincinnati, Cleveland, Indianapolis, St. Louis, and Toledo.