The Nile is a major north-flowing river in northeastern Africa. It flows into the Mediterranean Sea. The Nile is the longest river in Africa and has historically been considered the longest river in the world, though this has been contested by research suggesting that the Amazon River is slightly longer. Of the world's major rivers, the Nile is one of the smallest, as measured by annual flow in cubic metres of water. About 6,650 km (4,130 mi) long, its drainage basin covers eleven countries: the Democratic Republic of the Congo, Tanzania, Burundi, Rwanda, Uganda, Kenya, Ethiopia, Eritrea, South Sudan, Sudan, and Egypt. In particular, the Nile is the primary water source of Egypt, Sudan and South Sudan. Additionally, the Nile is an important economic river, supporting agriculture and fishing.

The Mediterranean Sea is a sea connected to the Atlantic Ocean, surrounded by the Mediterranean Basin and almost completely enclosed by land: on the north by Southern Europe and Anatolia, on the south by North Africa, and on the east by the Levant in West Asia. The Mediterranean has played a central role in the history of Western civilization. Geological evidence indicates that around 5.9 million years ago the Mediterranean was cut off from the Atlantic and was partly or completely desiccated over a period of some 600,000 years during the Messinian salinity crisis before being refilled by the Zanclean flood about 5.3 million years ago.