Nile Air is an Egyptian airline based at Cairo International Airport that operates scheduled services to destinations in Egypt and the Middle East, the Persian Gulf, Southern Europe, Asia and Africa. Nile Air is the largest private airline in Egypt and second only to Egyptair. It is a full-service carrier that operates scheduled services, using a fleet of Airbus A320-200s & Airbus A321-200s. In addition to operations from its hub at Cairo International Airport, the airline operates a smaller base from Alexandria's Borg El Arab Airport.

Cairo International Airport is the principal international airport of Cairo and the largest and busiest airport in Egypt. It serves as the primary hub for Egyptair and Nile Air as well as several other airlines. The airport is located in Heliopolis, to the northeast of Cairo around fifteen kilometres from the business area of the city and has an area of approximately 37 km2 (14 sq mi). It is the busiest airport in Africa, in terms of total passengers.