Niskayuna is a town in Schenectady County, New York, United States. The population was 23,278 at the 2020 census. The town is located in the southeast part of the county, east of the city of Schenectady, and is the easternmost town in the county.

Schenectady County is a county in the U.S. state of New York. As of the 2020 census, the population was 158,061. The county seat is Schenectady. The name is from a Mohawk language word meaning "on the other side of the pine lands," a term that originally applied to Albany. The county is part of the Capital District region of the state.