The 2006 No Mercy was the ninth No Mercy professional wrestling pay-per-view (PPV) event produced by World Wrestling Entertainment (WWE). It was held exclusively for WWE Talent from the promotion's SmackDown! brand division. The event took place on October 8, 2006, from the RBC Center in Raleigh, North Carolina. It was the final brand-exclusive No Mercy during the first brand extension, as brand-exclusive PPVs were discontinued following WrestleMania 23 in April 2007. It was also the last No Mercy to be SmackDown-exclusive until the 2016 event during the second brand extension when brand-exclusive PPVs returned.

The 2016 No Mercy was the 12th No Mercy professional wrestling pay-per-view (PPV) and livestreaming event produced by WWE. It was held exclusively for wrestlers from the promotion's SmackDown brand division. The event took place on October 9, 2016, at the Golden 1 Center in Sacramento, California. It was the first No Mercy held since 2008 and it was also the first SmackDown-exclusive No Mercy since 2006. This also made it the first No Mercy to livestream on WWE's online streaming service, the WWE Network, which launched in 2014. Unlike the majority of WWE's PPVs, No Mercy 2016 was not released on DVD or Blu-Ray.