The Nokia E61 is a mobile phone from the Eseries range, a S60 3rd Edition device targeting business users in the European market. It was announced as part of the new Eseries business line on 12 October 2005 along with the Nokia E60 and E70. As of Q4 2006, Cingular and Rogers Wireless deployed a similar yet restricted version designated the Nokia E62 in the North American and Brazilian markets. The E62 is substantially similar but without an 802.11 WiFi chipset or W-CDMA (UMTS) 3G support. E61 supports 900/1800/1900 bands, while E62 can operate in 850/900/1800/1900 in order to support American networks.

The Nokia Eseries consists of business-oriented smartphones running Symbian OS, with emphasis on enhanced connectivity and support for corporate e-mail push services, as well as enterprise-styled products and many featuring QWERTY keyboards. All devices have advanced office features through its S60 platform. Phones equipped with Wireless LAN also provide a VoIP client. Throughout the series' lifetime its main competitors were BlackBerry products from Research In Motion. The Eseries was marketed until 2011.