Nomusa Dube-Ncube is a South African politician and former diplomat who has been the 9th Premier of KwaZulu-Natal since August 2022. A member of the African National Congress, she is the first woman to hold the office.

The Premier of KwaZulu-Natal is the head of government of the KwaZulu-Natal province of South Africa. The current Premier of KwaZulu-Natal is Nomusa Dube-Ncube, a member of the African National Congress. She is the first elected woman to assume this position and took office on 10 August 2022.