North Branch Shamokin Creek is a tributary of Shamokin Creek in Columbia County and Northumberland County, Pennsylvania, United States. It is approximately 4.8 miles (7.7 km) long and flows through Conyngham Township in Columbia County and Mount Carmel Township in Northumberland County. The watershed of the creek has an area of 5.73 square miles (14.8 km2). The entirety of the creek is designated as an impaired waterbody due to metals from abandoned mine drainage. It is acidic, but its pH has been increasing. Underground mine complexes occur within the watershed. The creek has a permeable streambed and experiences flow loss.

Shamokin Creek is a tributary of the Susquehanna River in Northumberland County, Pennsylvania, in the United States. It is approximately 32.4 miles (52.1 km) long and flows through Mount Carmel, Mount Carmel Township, Coal Township, Shamokin, Ralpho Township, Shamokin Township, Snydertown, Upper Augusta Township, and Sunbury. The watershed of the creek has an area of 137 square miles (350 km2). It experiences significant impacts by abandoned mine drainage and many abandoned mine drainage discharges are in its watershed. Various other impairments also affect parts of the creek's watershed. Shamokin Creek is in the Appalachian Mountains section of the Ridge and Valley physiographic province. Rock formations consisting of sandstone, shale, and anthracite deposits occur in the watershed.