North Carolina Highway 150 (NC 150) is a primary state highway in the U.S. state of North Carolina. It serves the Foothills and Piedmont Triad areas of the state, connecting the cities of Shelby, Mooresville, Salisbury and Winston-Salem.

Shelby is a city in and the county seat of Cleveland County, North Carolina. It lies near the western edge of the Charlotte-Concord, NC-SC Combined Statistical Area. The population was 21,918 at the 2020 census.