North Carolina Highway 403 (NC 403) is a primary state highway located in U.S. State of North Carolina. The highway travels through Sampson, Duplin, and Wayne Counties between its southern terminus at U.S. Route 701 Business in Clinton and NC 55 in Williams. Between its termini, NC 403 connects to Interstate 40 (I-40) and Faison. The highway is primarily rural and predominantly travels through rural forests and farmlands. While signed in a north-south direction, NC 403 physically travels in a northeast-southwest direction along the duration of its route.

Sampson County is a county located in the U.S. state of North Carolina. As of the 2020 census, the population was 59,036. Its county seat is Clinton.