The Northwestern Turnpike is a historic road in West Virginia, important for being historically one of the major roads crossing the Appalachians, financed by the Virginia Board of Public Works in the 1830s. In modern times, west of Winchester, Virginia, U.S. Route 50 follows the path of the Northwestern Turnpike into West Virginia, whose major Corridor D project follows the western section of the original Northwestern Turnpike.

Claude "Claudius" Crozet was a soldier, educator, and civil engineer.