"Nothing Fails" is a song by American singer-songwriter Madonna from her ninth studio album, American Life (2003). Written by Madonna, Guy Sigsworth and Jem Griffiths, and produced by the singer along with Mirwais Ahmadzaï and Mark "Spike" Stent, it was released as the third single from the album on October 27, 2003. Originally demoed as "Silly Thing", "Nothing Fails" is a love song which has acoustic guitar chords and a gospel choir appearance. Lyrically, the song discusses a lover who is the one, and how their meeting was not just chance. A number of remixes of the song were done, with one of them being included on Madonna's remix album Remixed & Revisited (2003).

American Life is the ninth studio album by American singer Madonna. It was released on April 21, 2003, by Maverick and Warner Bros. Records. The album, produced by the singer and Mirwais Ahmadzaï, features references to many parts of American culture. The album is a concept album, with themes panning the American Dream and materialism. These themes reject the reputation Madonna held in the 1980s, earned by songs such as her 1984 Billboard Hot 100 number-two hit, "Material Girl". American Life is a folktronica and eurotechno album, influenced by acoustic music.