Nothing Sacred is a 1937 American Technicolor screwball comedy film directed by William A. Wellman, produced by David O. Selznick, and starring Carole Lombard and Fredric March with a supporting cast featuring Charles Winninger and Walter Connolly. Ben Hecht was credited with the screenplay based on the 1937 story "Letter to the Editor" by James H. Street, and an array of additional writers, including Ring Lardner Jr., Budd Schulberg, Dorothy Parker, Sidney Howard, Moss Hart, George S. Kaufman and Robert Carson made uncredited contributions.

Screwball comedy is a film subgenre of the romantic comedy genre that became popular during the Great Depression, beginning in the early 1930s and thriving until the early 1950s, that satirizes the traditional love story. It has secondary characteristics similar to film noir, distinguished by a female character who dominates the relationship with the male central character, whose masculinity is challenged, and the two engage in a humorous battle of the sexes.