Nothrotheriidae is a family of extinct ground sloths that lived from approximately 17.5 mya—10,000 years ago, existing for approximately 17.49 million years. Previously placed within the tribe Nothrotheriini or subfamily Nothrotheriinae within Megatheriidae, they are now usually placed in their own family, Nothrotheriidae. Nothrotheriids appeared in the Burdigalian, some 19.8 million years ago, in South America. The group includes the comparatively slightly built Nothrotheriops, which reached a length of about 2.75 metres (9.0 ft). While nothrotheriids were small compared to some of their megatheriid relatives, their claws provided an effective defense against predators, like those of larger anteaters today.

Ground sloths are a diverse group of extinct sloths in the mammalian superorder Xenarthra. Ground sloths varied widely in size, with the largest, belonging to genera Megatherium and Eremotherium, being around the size of elephants. Ground sloths are a paraphyletic group, as living tree sloths are thought to have evolved from ground sloth ancestors.