Notre-Dame Cathedral is the Roman Catholic Cathedral of Luxembourg City, in southern Luxembourg. It was originally a Jesuit church, and its cornerstone was laid in 1613. It is the only cathedral in Luxembourg.

Luxembourg, also known as Luxembourg City, is the capital city of Luxembourg and the country's most populous commune. Standing at the confluence of the Alzette and Pétrusse rivers in southern Luxembourg, the city lies at the heart of Western Europe, situated 213 km (132 mi) by road from Brussels, 372 km (231 mi) from Paris, and 209 km (130 mi) from Cologne. The city contains Luxembourg Castle, established by the Franks in the Early Middle Ages, around which a settlement developed.