Notre-Dame is a Neoclassical Catholic parish church in the town of Guebwiller, in the Haut-Rhin department of France. The church is classified as a monument historique by the French Ministry of Culture since 1841. The building is remarkable for its size and for the quality of its decoration; it is considered as the most important Neoclassical church in Alsace, and as an outstanding and most sumptuous example of early Neoclassical architecture.

Guebwiller is a commune in the Haut-Rhin département in Grand Est currently in north-eastern France. It was a sub-prefecture of the department until 2015.