Notre Dame College was a private Roman Catholic college in South Euclid, Ohio. Established in 1922 by the Sisters of Notre Dame as a women's college, it has been coeducational since January 2001. The Sisters of Notre Dame ended their sponsorship of the college in 2023. In February 2024, the college announced it would be closing at the end of the spring semester, with agreements in place for existing students to complete their degrees at partner colleges and universities.

South Euclid is a city in Cuyahoga County, Ohio, United States. It is an inner-ring suburb of Cleveland located on the city's east side. As of the 2020 census, the population was 21,883.