Novara railway station is the main station serving the city and comune of Novara, in the Piedmont region of northwestern Italy. Opened in 1854, it forms part of the Turin–Milan and is the origin point of the lines to Arona, to Alessandria, to Biella, Varallo, Domodossola and Luino.

Novara is the capital city of the province of Novara in the Piedmont region in northwest Italy, to the west of Milan. With 101,916 inhabitants, it is the second most populous city in Piedmont after Turin. It is an important crossroads for commercial traffic along the routes from Milan to Turin and from Genoa to Switzerland. Novara lies between the streams Agogna and Terdoppio in northeastern Piedmont, 50 km (31 mi) from Milan and 95 km (59 mi) from Turin. It is only 15 km (9.3 mi) distant from the river Ticino, which marks the border with Lombardy region.