Carbohydrate NMR spectroscopy is the application of nuclear magnetic resonance spectroscopy to structural and conformational analysis of carbohydrates. This method allows the scientists to elucidate s
Approximate scheme of NMR (blue) and other (green) techniques applied to carbohydrate structure elucidation, and information obtained (in boxes)
Comparative prediction of the 13C NMR spectrum of sucrose using various methods. Experimental spectrum is in the middle. Upper spectrum (black) was obtained by empirical routine. Lower spectra (red and green) were obtained by quantum-chemical calculations in PRIRODA and GAUSSIAN respectively. Included information: used theory level/basis set/solvent model, accuracy of prediction (linear correlation factor and root mean square deviation), calculation time on personal computer (blue).
Nuclear Overhauser effect
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The nuclear Overhauser effect is the transfer of nuclear spin polarization from one population of spin-active nuclei to another via cross-relaxation. A phenomenological definition of the NOE in nuclea
Nuclear magnetic resonance spectroscopy of carbohydrates
…Geminal between hydroxymethyl protons: 12 Hz NOEs are sensitive to interatomic distances, allowing their usage as a conformational probe, or proof of a glycoside bond formation. It's a common practice…
2D NOESY spectrum of codeine
Nuclear Overhauser effect
Homonuclear NMR techniques in carbohydrate studies.