Nuclear power in Switzerland is generated by three nuclear power plants, with a total of four operational reactors (see list below). Since 1985, nuclear power has been contributing approximately 40% of Switzerland's electrical energy. In 2022, it produced 23 terawatt-hours (TWh) of electricity, and accounted for 37% of the nation's gross electricity generation of 62 TWh, while 55% was produced by hydroelectric plants and 8% came from conventional thermal power stations and non-hydro renewable energy sources.

The Mühleberg Nuclear Power Plant is a formerly operational nuclear power plant in the Mühleberg municipality in the canton of Bern, Switzerland. Operated by BKW FMB Energie AG, the plant generated power from 6 November 1972 until 20 December 2019. Nuclear decommissioning of the plant began January 2020 and is currently forecasted to be completed by 2034.