Nuclear propulsion includes a wide variety of propulsion methods that use some form of nuclear reaction as their primary power source. The idea of using nuclear material for propulsion dates back to the beginning of the 20th century. In 1903 it was hypothesized that radioactive material, radium, might be a suitable fuel for engines to propel cars, planes, and boats. H. G. Wells picked up this idea in his 1914 fiction work The World Set Free. Many aircraft carriers and submarines currently use uranium fueled nuclear reactors that can provide propulsion for long periods without refueling. There are also applications in the space sector with nuclear thermal and nuclear electric engines which could be more efficient than conventional rocket engines.

A nuclear thermal rocket (NTR) is a type of thermal rocket where the heat from a nuclear reaction replaces the chemical energy of the propellants in a chemical rocket. In an NTR, a working fluid, usually liquid hydrogen, is heated to a high temperature in a nuclear reactor and then expands through a rocket nozzle to create thrust. The external nuclear heat source theoretically allows a higher effective exhaust velocity and is expected to double or triple payload capacity compared to chemical propellants that store energy internally.