Nurse Jackie is an American medical comedy-drama television series that aired on Showtime from June 8, 2009, to June 28, 2015. Set in New York City, the series follows Jackie Peyton, a drug-addicted emergency department nurse at the fictional All Saints' Hospital.

Emily "Eve" Best is an English actress and director. She is known for her television roles as Dr. Eleanor O'Hara in the Showtime series Nurse Jackie (2009–2013), First Lady Dolley Madison in the American Experience television special (2011), Monica Chatwin in the BBC miniseries The Honourable Woman (2014) and Princess Rhaenys Targaryen in HBO’s House of the Dragon. She also played Wallis Simpson in the 2010 film The King's Speech.