ONE 160: Ok vs. Lee 2 was a Combat sport event produced by ONE Championship that took place on August 26, 2022, at the Singapore Indoor Stadium in Kallang, Singapore.

One Championship is a multinational combat sports promotion founded on 14 July 2011 by Chatri Sityodtong and Victor Cui. Originally focused on mixed martial arts (MMA), ONE has since expanded to regularly hold events featuring Muay Thai, kickboxing, and submission grappling bouts, while also previously promoting boxing and Lethwei matches. One held its first event on 3 September 2011 at the Singapore Indoor Stadium, and has since held over 200 events across Asia.