OSS 117: Cairo, Nest of Spies is a 2006 French spy comedy film directed and co-written by Michel Hazanavicius in his feature directorial debut. Starring Jean Dujardin, Bérénice Bejo, and Aure Atika, the film has been widely praised for its cinematography, editing, and score. Set in 1955, the film follows the exploits of a French secret agent as he is sent to Cairo to investigate the disappearance of his best friend and fellow spy Jack Jefferson, only to stumble into a web of international intrigue.

Michel Hazanavicius is a French film director, screenwriter, editor, and producer. He is best known for his 2011 film, The Artist, which won the Academy Award for Best Picture at the 84th Academy Awards. It also won him the Academy Award for Best Director. He also directed spy film parodies OSS 117: Cairo, Nest of Spies (2006) and OSS 117: Lost in Rio (2009).