Oaxaca de Juárez, or simply Oaxaca, is the capital and largest city of the eponymous Mexican state of Oaxaca. It is the municipal seat for the surrounding municipality of Oaxaca. It is in the Centro District in the Central Valleys region of the state, in the foothills of the Sierra Madre at the base of the Cerro del Fortín, extending to the banks of the Atoyac River.

The Central Valleys of Oaxaca, also simply known as the Oaxaca Valley, is a geographic region located within the modern-day state of Oaxaca in southern Mexico. In an administrative context, it has been defined as comprising the districts of Etla, Centro, Zaachila, Zimatlán, Ocotlán, Tlacolula and Ejutla. The valley, which is located within the Sierra Madre Mountains, is shaped like a distorted and almost upside-down “Y,” with each of its arms bearing specific names: the northwestern Etla arm, the central southern Valle Grande, and the Tlacolula arm to the east. The Oaxaca Valley was home to the Zapotec civilization, one of the earliest complex societies in Mesoamerica, and the later Mixtec culture. A number of important and well-known archaeological sites are found in the Oaxaca Valley, including Monte Albán, Mitla, San José Mogote and Yagul. Today, the capital of the state, the city of Oaxaca, is located in the central portion of the valley.