Oberhausen-Holten is a railway station in Oberhausen, North Rhine-Westphalia, Germany. The station is located on the Arnhem-Oberhausen railway. The train services are operated by Deutsche Bahn and Abellio Deutschland.

The Oberhausen–Arnhem railway is a two-track, electrified main line railway running close to the lower Rhine from Oberhausen via Wesel, Emmerich and the German–Dutch border to Arnhem and forms part of the line between the Ruhr and Amsterdam. The line was opened by the Cologne-Minden Railway Company in 1856 and is one of the oldest lines in Germany.