The city of Smyrna and surrounding areas were under Greek military occupation from 15 May 1919 until 9 September 1922. The Allied Powers authorized the occupation and creation of the Zone of Smyrna during negotiations regarding the partition of the Ottoman Empire to protect the ethnic Greek population living in and around the city. The Greek landing on 15 May 1919 was celebrated by the substantial local Greek population but quickly resulted in ethnic violence in the area. This violence decreased international support for the occupation and led to a rise in Turkish nationalism. The high commissioner of Smyrna, Aristeidis Stergiadis, firmly opposed discrimination against the Turkish population by the administration; however, ethnic tensions and discrimination remained. Stergiadis also began work on projects involving resettlement of Greek refugees, the foundations for a university, and some public health projects. Smyrna was a major base of operations for Greek troops in Anatolia during the Greco-Turkish War (1919–1922).

Aristeidis Stergiadis was the Greek high commissioner, or governor-general, of Smyrna during the Greek occupation of the city from 1919 to 1922.