The Office of the Prime Minister is the central executive agency in the Government of the Kingdom of Thailand. It is classified as a cabinet department and is led by a permanent secretary. Its main responsibility is to assist the Prime Minister of Thailand in the role of head of government and chair of the Cabinet of Thailand.

The Government of Thailand, or formally the Royal Thai Government, is the unitary government of the Kingdom of Thailand. The country emerged as a modern nation state after the foundation of the Chakri Dynasty and the city of Bangkok in 1782. The Revolution of 1932 brought an end to absolute monarchy and replaced it with a constitutional monarchy.