The Office of the Secretary of State for Scotland, often referred to as the Scotland Office, is a department of His Majesty's Government headed by the Secretary of State for Scotland and responsible for Scottish affairs that lie within HM Government's responsibility.

The secretary of state for Scotland, also referred to as the Scottish secretary, is a secretary of state in the Government of the United Kingdom, with responsibility for the Scotland Office. The incumbent is a member of the Cabinet of the United Kingdom. Much of the Secretary of State for Scotland's responsibility transferred to the office of the First Minister of Scotland upon the re–establishment of both the Scottish Government and Scottish Parliament in 1999 following the Scotland Act 1998.