State Route 19 is a north–south route in northern and central Ohio. Its southern terminus is at U.S. Route 42 in the unincorporated village of Williamsport, and its northern terminus is at State Route 2 north of Oak Harbor.

State Route 2, formerly known as Inter-county Highway 2 until 1921 and State Highway 2 in 1922, is an east–west highway crossing most of northern Ohio. Its western terminus is at the Indiana state line near Hicksville where the route becomes Indiana State Road 37 which continues to Fort Wayne, Indiana. The eastern terminus of the route is in Painesville Township in Lake County at U.S. Route 20 (US 20).