State Route 2, formerly known as Inter-county Highway 2 until 1921 and State Highway 2 in 1922, is an east–west highway crossing most of northern Ohio. Its western terminus is at the Indiana state line near Hicksville where the route becomes Indiana State Road 37 which continues to Fort Wayne, Indiana. The eastern terminus of the route is in Painesville Township in Lake County at U.S. Route 20 (US 20).

State Road 37 (SR 37) is a major route in the U.S. state of Indiana, running as a four-lane divided highway for 110 miles of its course.