State Route 45 is a north–south state highway in the northeastern portion of the U.S. state of Ohio. Its southern terminus is at the State Route 7/State Route 39 concurrency in Wellsville, and its northern terminus is at State Route 531 about three miles (4.8 km) west of Ashtabula.

U.S. Route 30 (US 30) is a United States Numbered Highway that runs from Astoria, Oregon, to Atlantic City, New Jersey. In the state of Ohio, it is a major, 245-mile-long (394 km), east–west highway that runs through the northern section of the state. Overall, the highway runs through rural areas dominated by farm fields or woodlands; some segments are urban in character in the Mansfield and Canton areas.