The Ohio Turnpike, officially the James W. Shocknessy Ohio Turnpike, is a controlled-access toll road in the U.S. state of Ohio, serving as a primary corridor between Chicago and Pittsburgh. The road runs east–west for 241 miles (388 km) in the northern section of the state, with the western end at the Indiana–Ohio border near Edon where it meets the Indiana Toll Road, and the eastern end at the Ohio–Pennsylvania border near Petersburg, where it meets the Pennsylvania Turnpike. The road is owned and maintained by the Ohio Turnpike and Infrastructure Commission (OTIC), headquartered in Berea.

Interstate 280 (I-280) is a 12.41-mile-long (19.97 km) auxiliary Interstate Highway in Ohio that connects I-75 in northeast Toledo with I-80/I-90 southeast of the city in northeastern Wood County. Built between 1955 and 1959, the route was originally part of the Detroit–Toledo Expressway. Although first designated in 1959, the highway originally contained several at-grade intersections and other features which left it substandard to the Interstate Highway System until 1990. Further construction in 2007 built a new crossing of the Maumee River, replacing an outdated drawbridge. The highway serves as an easterly bypass of the Toledo metropolitan area, passing through the communities of Northwood and Oregon. It is one of two auxiliary Interstate Highways serving Toledo, the other being I-475.