Ohio University Chillicothe is a regional campus of Ohio University in Chillicothe, Ohio. Founded in 1946, OHIO Chillicothe campus is the first of Ohio University's regional campuses and the first regional campus in the state. It is located 45 miles (72 km) south of the state capital of Columbus. As of 2019, it has an enrollment of approximately 1,500 students.

Ohio University is a public research university in Athens, Ohio, United States. The first university chartered by an Act of Congress and the first to be chartered in Ohio, the university was chartered in 1787 by the Congress of the Confederation and subsequently approved for the territory in 1802 and state in 1804, opening for students in 1809.