Oklahoma Panhandle State University (OPSU) is a public college in Goodwell, Oklahoma. OPSU is a baccalaureate degree-granting institution. General governance of the institution is provided by the Board of Regents of the Oklahoma Agricultural and Mechanical Colleges. Academic programs and financial support are authorized and coordinated through the Oklahoma State Regents for Higher Education.

Goodwell is a town in Texas County, Oklahoma, United States. As of the 2020 census, the town's population was 951. Goodwell is home to Oklahoma Panhandle State University.